Ethereum News Update: Ethereum ETFs See $141M Inflows as Bullish Pattern Signals Potential $4,500 Rally

On October 21, 2025, Ethereum (ETH) hovered around $3,850 as U.S. spot ETFs saw renewed inflows after three consecutive days of outflows, hinting at a possible short-term recovery for the asset. This movement came after net inflows reached $141.6 million into

ETFs, with Fidelity’s FETH drawing $59.07 million and BlackRock’s ETHA bringing in $42.46 million, as reported by a . Grayscale’s Mini and products also attracted $22.58 million and $13.14 million, respectively, according to . Despite the recent dip, Ethereum’s 24-hour trading volume jumped 35.2% to $45.8 billion, while derivatives trading soared 57.3% to $114.2 billion, reflecting a resurgence in speculative activity, the crypto.news article noted.

Technical analysis indicates that Ethereum is currently consolidating and may be preparing for a breakout. The asset is trading below the Bollinger Band’s midline at $4,146, facing resistance at $4,720 and finding support near $3,563. The relative strength index (RSI) stands at 41.15, pointing to bearish momentum but not yet signaling an oversold market, according to crypto.news. Analysts observe a bull flag pattern emerging after Ethereum’s climb from $2,500 in April to $4,950 in August, with the 200-day EMA at $3,580 serving as a key support level, as highlighted by

. If Ethereum can break and hold above the $4,500 resistance, it could aim for the $4,600–$5,000 range, in line with previous rebounds from the $3,900 average on the MVRV indicator, the same analysis suggests.

Growing institutional interest is strengthening Ethereum’s long-term outlook. JPMorgan’s planned initiative to let institutional clients use Ethereum as collateral for loans by the end of the year could boost structural demand, according to

. In addition, Ethereum’s network welcomed 16,000 new developers in 2025—the most among major blockchain ecosystems—further cementing its position in decentralized applications and staking, the CoinEdition report added. On the macroeconomic side, investors are watching the Federal Reserve’s rate decision on October 28–29, with markets currently expecting a 95% chance of a 25-basis-point rate cut. A dovish move could relieve pressure on risk assets like cryptocurrencies, while a more hawkish approach might trigger renewed selling, crypto.news warned.

Nonetheless, short-term challenges persist. Ethereum needs to stay above $3,500 to keep the bull flag intact; falling below this level could lead to a correction toward the $3,000–$3,200 range, The Currency Analytics warned. Overall market sentiment will also depend on the pace of ETF inflows and broader economic indicators. At present, Ethereum’s technical and fundamental backdrop supports a potential rise toward $4,500 by the end of October, with institutional activity and macro trends likely to influence its path, according to

.